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People
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Idan Segev
PI, Head of Lab
Neurons – these aesthetic elementary microchips of the brain and their
synapses change as they receive and transmit information. This enables us to
learn and adapt to the complicated environment around us, have new ideas
and create new “brain inspired” learning machines, Art and Science. A deep
understanding of a computing and learning system such as our own brain
requires understanding the computational and plastic functions of its basic
components – the nerve cells, their synapses and the specific neuronal
networks that they form. Our laboratory utilizes detailed computer simulations
of detailed cortical circuits (as part of the Blue Brain Project), big data and
machine learning approaches, and analytic methods to study the relationships
between neurons’ geometry, network connectivity/plasticity and network
dynamics. A recent challenge at the lab. is to understand the unique
properties of Human cortical neurons and cortical circuits, measured in fresh
human tissue obtained following brain operations, and in close collaboration
with several international groups (under the “Cell Census” NIH BRAIN
Initiative).
Email: idan@lobster.ls.huji.ac.il
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David Beniaguev
Postdoc
Single biological neurons as temporally-precise spatio-temporal pattern
recognizers. Trying to understand how single neurons perform computations,
in particular, how dendrites allow neurons to perform complex spatial
computations and whether they also allow the neuron to utilize the temporal
dimension as an additional axis for packing even more useful computations
inside a single neuron.
Email: david.beniaguev@mail.huji.ac.il
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Netanel Ofer
Postdoc
Netanel is a computational neuroanatomist focused on deciphering the
functional principles of neurons. He currently utilizes advanced high-resolution
EM-based models of dendrites in the lab of Prof. Idan Segev. Previously, as a
postdoctoral researcher with Prof. Rafael Yuste at Columbia University,
Netanel explored the morphology and activity of dendritic spines and axons.
He earned both his undergraduate and graduate degrees from the Faculty of
Engineering at Bar Ilan University, specializing in computational models of
axonal structures.
Email: netanel.ofer@mail.huji.ac.il
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Toviah Moldwin
Postdoc
My research has focused on understanding plasticity and learning in models
of the single neuron. I am interested in the relationship between real biological
neurons and the simple mathematical nodes found in artificial neural
networks. I have also worked on understanding how calcium mediates
plasticity and learning. I am currently working on understanding the basis of
stimulus selectivity in the brain using spiking neural network models.
Email: tmoldwin@gmail.com
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Ido Izenbud
Ph.D student
Exploring the computational and learning capabilities of biological neurons
and networks through deep learning, aiming to reveal key aspects of neural
computation at both individual and network levels.
Email: ido.aizenbud@mail.huji.ac.il
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Sapir Shapira
Ph.D student
Study the theoretical aspects of neural computation through time, at the single
neuron and the network level. This theoretical work is done via collaborations
creating high spatio-temporal resolution datasets, allowing us to ask questions
at much finer details.
Email: sapir.shapira@mail.huji.ac.il
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Michal Leci
Administrative Assistant and Budgets Coordinator
Tel: +972-2-6586989
Email: michal.leci@mail.huji.ac.il
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ALUMNI
Ph.D. students and thesis subjects
2002 - |
Irit Nowik, iritn@alice.nc.huji.ac.il
"The game neurons play" (co-supervised with S. Zamir) |
2001 - |
Ron Jortner, ronijort@alice.nc.huji.ac.il (co-supervised with G. Laurent)
"The role of the mushroom body and lateral protocerebrum in insect learning, memory and perception"
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2003 - |
Anat Yaron-Jakoubovitch, anatyar@lobster.ls.huji.ac.il (co-director Prof. Y. Yarom) "Stochastic Fluctuations in Voltage of Pyramidal Neurons"
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2006 - |
Leora Manheim, leora@lobster.ls.huji.ac.il (co-supervised Prof. bert Sakmmann)
"Understanding information processing in the barrel cortex via merging in vitro and in vivo data in a detailed modeling study"
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2002 - | Yoav Banitt, ybanitt@lobster.ls.huji.ac.il "Realistic models of cortical spiny stellate cells"
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2003 - | Lital Bar Ilan, lital@lobster.ls.huji.ac.il (co-director Prof. Y. Yarom) "The Involvement of Dendritic Calcium Spikes in Synaptic Plasticity of Cortical Pyramidal Neurons"
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2002 - 2006 | Ithai Rabinowitch, ithai@lobster.ls.huji.ac.il
"The Coupling of the State of a Neuron to its Environment Via Homeostatic Synaptic Plasticity at Large Time Scales"
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1999 - 2002 | Galit Fuhrman, galit.fuhrmann@weizmann.ac.il (co-supervised with M. Tsodyks). "The information content of depressing synapses"
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1994 - 2001 | Puah Mann-Metzer, puah@lobster.ls.huji.ac.il (co-supervised with Y. Yarom). "Characterization of the inhibitory system in the cerebellar cortex"
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1994 - 2001 | Elad Schniedman, elads@princeton.edu (co-supervised with N. Tishbi). "The effect of neuronal noise on information capacity of neurons"
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1993 - 2001 | Michael London, mikilon@lobster.ls.huji.ac.il "Defining synaptic efficacy using theoretic information tools"
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1993 - 1999 | Yoram Gutfreund, yoram@leland.stanford.edu (co-supervised with Y. Yarom and B. Hochner). "Motor control of the octopus arm"
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1993 - 1999 | Dana Cohen (co-supervised with Y. Yarom). "Exploring cerebellar circuitry using optical imaging"
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1992 - 1998 | Moshe Rav-Acha (co-supervised with H. Bergman and Y. Yarom). "Characterization of neurons in the globus palidus in vitro"
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1992 - 1996 | Hagai Agmon-Snir "A new method for analyzing dendritic transients"
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1992 - 1998 | Itzchak Aharon (co-supervised with Y. Yarom). "Systematic characterization of dendritic morphology"
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1992 - 1996 | Yair Manor (co-supervised with Y. Yarom). "On the subthreshold membrane voltage oscillations in olivary neurons"
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1994 - 1998 | Moshe Rapp (co-supervised with Y. Yarom). "Experimental and theoretical study of cerebellar Purkinje cells"
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1990 - 1995 | Ron Nitzan (co-supervised with Y. Yarom). "Physiology and cable models of vagal motoneurons"
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M.Sc. students
2006 - | Shaul Druckmann, drucks@lobster.ls.huji.ac.il
"Dynamics of neural networks - interaction of network architecture and single neuron behavior"
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2006 - | Albert Gideon, agidon20@lobster.ls.huji.ac.il
"Spike-timing-dependent plasticity in dendritic neurons"
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2006 - | Etay Hay, etay.hay@mail.huji.ac.il
"Signal processing in cortical microcircuits"
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2000 - 2002 | Yoav Banitt, ybanitt@lobster.ls.huji.ac.il "Realistic models of cortical spiny stellate cells"
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1999 - 2002 | Nitzan Kol, nkol@lobster.ls.huji.ac.il "Synchrony in electrically-coupled neural nets"
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1997 - 2000 | Gal Eliraz "Reduced models of neurons"
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1997 - 2000 | Oz Kahana, ozkahana@hotmail.com "Motion computation with dendrites"
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1990 - 1992 | Yoram Gutfreund (co-supervised with Y. Yarom). "Subthreshold oscillations in cortical pyramidal neurons"
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1988 - 1990 | Michael Nevo "Analytical model for the effect of dendritic spines on the integrative properties of neurons"
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